7LAP

Crystal structure of aminoglycoside acetyltransferase AAC(3)-Xa

7LAP の概要

• エントリーDOI: 10.2210/pdb7lap/pdb
• 分子名称: Aminoglycoside N(3)-acetyltransferase, D(-)-TARTARIC ACID, FORMIC ACID, ... (5 entities in total)
• 機能のキーワード: aac(3)-xa, resistance, csgid, transferase, center for structural genomics of infectious diseases, national institute of allergy and infectious diseases, niaid
• 由来する生物種: Streptomyces griseus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 64535.18

構造登録者

Stogios, P.J.,Skarina, T.,Kim, Y.,Di Leo, R.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2021-01-06, 公開日: 2021-02-03, 最終更新日: 2023-10-18)

• 主引用文献: Stogios, P.J.,Bordeleau, E.,Xu, Z.,Skarina, T.,Evdokimova, E.,Chou, S.,Diorio-Toth, L.,D'Souza, A.W.,Patel, S.,Dantas, G.,Wright, G.D.,Savchenko, A.; Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family.; Commun Biol, 5:263-263, 2022; PubMed: 35338238; DOI: 10.1038/s42003-022-03219-w

実験手法

X-RAY DIFFRACTION (2.04 Å)