7L4V
C-terminal bZIP domain of human C/EBPbeta Bound to DNA with Consensus Recognition with GT Mismatch
Summary for 7L4V
Entry DOI | 10.2210/pdb7l4v/pdb |
Descriptor | CCAAT/enhancer-binding protein beta, DNA Strand 1, DNA Strand 2, ... (5 entities in total) |
Functional Keywords | bzip transciption factor dna methylation cpa methylation protein-dna complex, transcription, transcription-dna complex, g-t dna mismatch, transcription/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 28771.25 |
Authors | Horton, J.R.,Cheng, X. (deposition date: 2020-12-21, release date: 2021-11-03, Last modification date: 2023-10-18) |
Primary citation | Yang, J.,Horton, J.R.,Akdemir, K.C.,Li, J.,Huang, Y.,Kumar, J.,Blumenthal, R.M.,Zhang, X.,Cheng, X. Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations. Nucleic Acids Res., 49:5084-5094, 2021 Cited by PubMed: 33877329DOI: 10.1093/nar/gkab276 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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