7L4I

Crystal structure of a substrate-trapping variant of PPM1H phosphatase

Summary for 7L4I

Entry DOI	10.2210/pdb7l4i/pdb
Descriptor	Protein phosphatase 1H, MAGNESIUM ION (3 entities in total)
Functional Keywords	rab gtpase, lrrk2 kinase, pp2c/ppm family, membrane trafficking, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	100733.15
Authors	Khan, A.R.,Waschbusch, D. (deposition date: 2020-12-19, release date: 2021-08-04, Last modification date: 2023-10-18)
Primary citation	Waschbusch, D.,Berndsen, K.,Lis, P.,Knebel, A.,Lam, Y.P.,Alessi, D.R.,Khan, A.R. Structural basis for the specificity of PPM1H phosphatase for Rab GTPases. Embo Rep., 22:e52675-e52675, 2021 Cited by PubMed: 34580980 DOI: 10.15252/embr.202152675 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.58 Å)

Structure validation