7KZH

Zinc finger antiviral protein (ZAP) central domain

Summary for 7KZH

Entry DOI	10.2210/pdb7kzh/pdb
Descriptor	Zinc finger CCCH-type antiviral protein 1, ZINC ION (3 entities in total)
Functional Keywords	restriction factor, antiviral protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	23686.30
Authors	Pornillos, O.P. (deposition date: 2020-12-10, release date: 2021-12-15, Last modification date: 2023-01-11)
Primary citation	Xue, G.,Braczyk, K.,Goncalves-Carneiro, D.,Dawidziak, D.M.,Sanchez, K.,Ong, H.,Wan, Y.,Zadrozny, K.K.,Ganser-Pornillos, B.K.,Bieniasz, P.D.,Pornillos, O. Poly(ADP-ribose) potentiates ZAP antiviral activity. Plos Pathog., 18:e1009202-e1009202, 2022 Cited by PubMed: 35130321 DOI: 10.1371/journal.ppat.1009202 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.49 Å)

Structure validation