7KYH

Botulism Neurooxin Light Chain A app form

Summary for 7KYH

• Entry DOI: 10.2210/pdb7kyh/pdb
• Descriptor: Bont/A1, ZINC ION, N-[(3,5-dichlorophenyl)sulfonyl]-L-phenylalanyl-N-hydroxy-L-valinamide (3 entities in total)
• Functional Keywords: bont, toxin
• Biological source: Clostridium botulinum
• Total number of polymer chains: 4
• Total formula weight: 193323.33

Authors

Ortega, M.E.,Salzameda, N.T. (deposition date: 2020-12-07, release date: 2021-04-14, Last modification date: 2023-10-18)

• Primary citation: Amezcua, M.,Cruz, R.S.,Ku, A.,Moran, W.,Ortega, M.E.,Salzameda, N.T.; Discovery of Dipeptides as Potent Botulinum Neurotoxin A Light-Chain Inhibitors.; Acs Med.Chem.Lett., 12:295-301, 2021; PubMed: 33603978; DOI: 10.1021/acsmedchemlett.0c00674

Experimental method

X-RAY DIFFRACTION (2.91 Å)