7KXC

The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, sodium ion at the metal coordination site and benzimidazole (BZI) at the enzyme beta-site at 1.30 Angstrom resolution. One of the beta-Q114 rotamer conformations allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring

7KXC の概要

• エントリーDOI: 10.2210/pdb7kxc/pdb
• 関連するPDBエントリー: 4HPX 6X0C
• 分子名称: Tryptophan synthase alpha chain, SODIUM ION, Tryptophan synthase beta chain, ... (11 entities in total)
• 機能のキーワード: inhibitor, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Salmonella enterica subsp. enterica serovar Typhimurium; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 73160.45

構造登録者

Hilario, E.,Dunn, M.F.,Mueller, L.J. (登録日: 2020-12-03, 公開日: 2021-12-15, 最終更新日: 2023-10-18)

• 主引用文献: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, sodium ion at the metal coordination site and benzimidazole (BZI) at the enzyme beta-site at 1.30 Angstrom resolution. One of the beta-Q114 rotamer conformations allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring.; To be Published,

実験手法

X-RAY DIFFRACTION (1.51 Å)