7KVV
Crystal structure of Squash RNA aptamer in complex with DFHBI-1T
Summary for 7KVV
Entry DOI | 10.2210/pdb7kvv/pdb |
Descriptor | Squash RNA aptamer bound to DFHO, MAGNESIUM ION, (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, ... (4 entities in total) |
Functional Keywords | fluorogenic aptamer, adenine riboswitch, rna |
Biological source | synthetic construct |
Total number of polymer chains | 1 |
Total formula weight | 27316.73 |
Authors | Truong, L.,Ferre-D'Amare, A.R. (deposition date: 2020-11-28, release date: 2022-01-19, Last modification date: 2023-10-18) |
Primary citation | Truong, L.,Kooshapur, H.,Dey, S.K.,Li, X.,Tjandra, N.,Jaffrey, S.R.,Ferre-D'Amare, A.R. The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold. Nat.Chem.Biol., 18:191-198, 2022 Cited by PubMed: 34937911DOI: 10.1038/s41589-021-00931-2 PDB entries with the same primary citation |
Experimental method |
Structure validation
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