7KUW

High-throughput design and refinement of stable proteins using sequence-only models

7KUW の概要

• エントリーDOI: 10.2210/pdb7kuw/pdb
• 分子名称: Sequence-Based Designed Protein nmt_0994_guided_02 (1 entity in total)
• 機能のキーワード: de novo designed, neural network, evaluator model, deep network hallucination, de novo protein
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 7193.41

構造登録者

Bera, A.K.,Stewart, L.,Kang, A.S.,Baker, D. (登録日: 2020-11-25, 公開日: 2021-12-15, 最終更新日: 2024-04-03)

• 主引用文献: Singer, J.M.,Novotney, S.,Strickland, D.,Haddox, H.K.,Leiby, N.,Rocklin, G.J.,Chow, C.M.,Roy, A.,Bera, A.K.,Motta, F.C.,Cao, L.,Strauch, E.M.,Chidyausiku, T.M.,Ford, A.,Ho, E.,Zaitzeff, A.,Mackenzie, C.O.,Eramian, H.,DiMaio, F.,Grigoryan, G.,Vaughn, M.,Stewart, L.J.,Baker, D.,Klavins, E.; Large-scale design and refinement of stable proteins using sequence-only models.; Plos One, 17:e0265020-e0265020, 2022; PubMed: 35286324; DOI: 10.1371/journal.pone.0265020

実験手法

X-RAY DIFFRACTION (2.43 Å)