7KUO
FANA modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G
Summary for 7KUO
Entry DOI | 10.2210/pdb7kuo/pdb |
Descriptor | RNA (5'-R((LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(GFL))-3'), DIGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | rna, nonenzymatic rna extension |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 10567.97 |
Authors | Fang, Z.,Giurgiu, C.,Szostak, J.W. (deposition date: 2020-11-25, release date: 2021-09-08, Last modification date: 2023-10-18) |
Primary citation | Giurgiu, C.,Fang, Z.,Aitken, H.R.M.,Kim, S.C.,Pazienza, L.,Mittal, S.,Szostak, J.W. Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis. Angew.Chem.Int.Ed.Engl., 60:22925-22932, 2021 Cited by PubMed: 34428345DOI: 10.1002/anie.202109714 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.281 Å) |
Structure validation
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