7KS9

Cryo-EM structure of prefusion SARS-CoV-2 spike glycoprotein in complex with 910-30 Fab

7KS9 の概要

• エントリーDOI: 10.2210/pdb7ks9/pdb
• EMDBエントリー: 23016
• 分子名称: 910-30 Fab light chain, 910-30 Fab heavy chain, Spike glycoprotein, ... (5 entities in total)
• 機能のキーワード: neutralizing antibody, fusion protein, spike glycoprotein, covid-19, rbd, viral protein, immune system, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 486963.44

構造登録者

Cerutti, G.,Shapiro, L. (登録日: 2020-11-21, 公開日: 2021-02-10, 最終更新日: 2022-11-09)

• 主引用文献: Banach, B.B.,Cerutti, G.,Fahad, A.S.,Shen, C.H.,Oliveira De Souza, M.,Katsamba, P.S.,Tsybovsky, Y.,Wang, P.,Nair, M.S.,Huang, Y.,Francino-Urdaniz, I.M.,Steiner, P.J.,Gutierrez-Gonzalez, M.,Liu, L.,Lopez Acevedo, S.N.,Nazzari, A.F.,Wolfe, J.R.,Luo, Y.,Olia, A.S.,Teng, I.T.,Yu, J.,Zhou, T.,Reddem, E.R.,Bimela, J.,Pan, X.,Madan, B.,Laflin, A.D.,Nimrania, R.,Yuen, K.Y.,Whitehead, T.A.,Ho, D.D.,Kwong, P.D.,Shapiro, L.,DeKosky, B.J.; Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses.; Cell Rep, 37:109771-109771, 2021; PubMed: 34587480; DOI: 10.1016/j.celrep.2021.109771

実験手法

ELECTRON MICROSCOPY (4.75 Å)