7KQX

MIF Y99C homotrimeric mutant

Summary for 7KQX

• Entry DOI: 10.2210/pdb7kqx/pdb
• Descriptor: Macrophage migration inhibitory factor, SULFATE ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: mif, mutant, isomerase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 38855.15

Authors

Manjula, R.,Georgios, P.,Lolis, E.J. (deposition date: 2020-11-18, release date: 2022-01-19, Last modification date: 2023-10-25)

• Primary citation: Skeens, E.,Pantouris, G.,Shah, D.,Manjula, R.,Ombrello, M.J.,Maluf, N.K.,Bhandari, V.,Lisi, G.P.,Lolis, E.J.; A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies.; Front Mol Biosci, 9:783669-783669, 2022; PubMed: 35252348; DOI: 10.3389/fmolb.2022.783669

Experimental method

X-RAY DIFFRACTION (1.6 Å)