7KQR

A 1.89-A resolution substrate-bound crystal structure of heme-dependent tyrosine hydroxylase from S. sclerotialus

Summary for 7KQR

• Entry DOI: 10.2210/pdb7kqr/pdb
• Descriptor: Heme-dependent L-tyrosine hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, TYROSINE, ... (6 entities in total)
• Functional Keywords: heme-binding enzyme, l-tyrosine hydroxylase, oxidoreductase
• Biological source: Streptomyces sclerotialus
• Total number of polymer chains: 2
• Total formula weight: 71295.06

Authors

Wang, Y.,Shin, I.,Liu, A. (deposition date: 2020-11-17, release date: 2021-03-31, Last modification date: 2024-04-03)

• Primary citation: Wang, Y.,Davis, I.,Shin, I.,Xu, H.,Liu, A.; Molecular Rationale for Partitioning between C-H and C-F Bond Activation in Heme-Dependent Tyrosine Hydroxylase.; J.Am.Chem.Soc., 143:4680-4693, 2021; PubMed: 33734681; DOI: 10.1021/jacs.1c00175

Experimental method

X-RAY DIFFRACTION (1.89 Å)