7KNY

The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/California) in complex with SJ000988528

Summary for 7KNY

• Entry DOI: 10.2210/pdb7kny/pdb
• Related: 7K87
• Descriptor: Protein PA-X, MANGANESE (II) ION, 2-(2-fluorophenyl)-5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-3,6-dihydropyrimidine-4-carboxamide, ... (6 entities in total)
• Functional Keywords: nuclease, influenza, inhibitor resistance, viral protein, hydrolase
• Biological source: Influenza A virus; More
• Total number of polymer chains: 1
• Total formula weight: 24506.53

Authors

Cuypers, M.G.,Slavish, P.J.,Jayaraman, S.,White, S.W. (deposition date: 2020-11-06, release date: 2021-11-10, Last modification date: 2023-10-18)

• Primary citation: Cuypers, M.G.,Slavish, P.J.,Jayaraman, S.,White, S.W.; The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/California) in complex with SJ000988528; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.48 Å)