7KNG

2.10A resolution structure of independent Phosphoglycerate mutase from C. elegans in complex with a macrocyclic peptide inhibitor (Ce-2 Y7F)

7KNG の概要

• エントリーDOI: 10.2210/pdb7kng/pdb
• 分子名称: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, DTY-ASP-TYR-PRO-GLY-ASP-PHE-CYS-TYR-LEU-TYR-GLY-THR-CYS, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: phosphoglycerate mutase, ipglycermide, peptide inhibitors, metal ion binding, isomerase
• 由来する生物種: Caenorhabditis elegans; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 122417.35

構造登録者

Lovell, S.,Kashipathy, M.M.,Battaile, K.P.,Weidmann, M.,Dranchak, P.,Aitha, M.,Queme, B.,Collmus, C.D.,Kanter, L.,Lamy, L.,Tao, D.,Rai, G.,Suga, H.,Inglese, J. (登録日: 2020-11-04, 公開日: 2021-04-07, 最終更新日: 2023-10-18)

• 主引用文献: Wiedmann, M.,Dranchak, P.K.,Aitha, M.,Queme, B.,Collmus, C.D.,Kashipathy, M.M.,Kanter, L.,Lamy, L.,Rogers, J.M.,Tao, D.,Battaile, K.P.,Rai, G.,Lovell, S.,Suga, H.,Inglese, J.; Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases.; J.Biol.Chem., 296:100628-100628, 2021; PubMed: 33812994; DOI: 10.1016/j.jbc.2021.100628

実験手法

X-RAY DIFFRACTION (2.1 Å)