7KNF
1.80A resolution structure of independent Phosphoglycerate mutase from C. elegans in complex with a macrocyclic peptide inhibitor (Ce-1 NHOH)
Summary for 7KNF
Entry DOI | 10.2210/pdb7knf/pdb |
Descriptor | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, DTY-ASP-TYR-PRO-GLY-ASP-HIS-CYS-TYR-LEU-TYR-GLY-THR, ZINC ION, ... (6 entities in total) |
Functional Keywords | phosphoglycerate mutase, ipglycermide, peptide inhibitors, metal ion binding, isomerase |
Biological source | Caenorhabditis elegans More |
Total number of polymer chains | 4 |
Total formula weight | 122731.89 |
Authors | Lovell, S.,Kashipathy, M.M.,Battaile, K.P.,Weidmann, M.,Dranchak, P.,Aitha, M.,Queme, B.,Collmus, C.D.,Kanter, L.,Lamy, L.,Tao, D.,Rai, G.,Suga, H.,Inglese, J. (deposition date: 2020-11-04, release date: 2021-04-07, Last modification date: 2023-11-15) |
Primary citation | Wiedmann, M.,Dranchak, P.K.,Aitha, M.,Queme, B.,Collmus, C.D.,Kashipathy, M.M.,Kanter, L.,Lamy, L.,Rogers, J.M.,Tao, D.,Battaile, K.P.,Rai, G.,Lovell, S.,Suga, H.,Inglese, J. Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases. J.Biol.Chem., 296:100628-100628, 2021 Cited by PubMed: 33812994DOI: 10.1016/j.jbc.2021.100628 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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