7KN3

Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab

7KN3 の概要

• エントリーDOI: 10.2210/pdb7kn3/pdb
• 分子名称: Spike protein S1, S-B8 Fab heavy chain, S-B8 Fab light chain, ... (8 entities in total)
• 機能のキーワード: sars-cov-2, antibody, spike, coronavirus, covid-19, immune system, viral protein-immune system complex, phage display, pre-pandemic, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 148617.89

構造登録者

Liu, H.,Zhu, X.,Wilson, I.A. (登録日: 2020-11-04, 公開日: 2021-09-22, 最終更新日: 2023-10-18)

• 主引用文献: Qiang, M.,Ma, P.,Li, Y.,Liu, H.,Harding, A.,Min, C.,Wang, F.,Liu, L.,Yuan, M.,Ji, Q.,Tao, P.,Shi, X.,Li, Z.,Li, T.,Wang, X.,Zhang, Y.,Wu, N.C.,Lee, C.D.,Zhu, X.,Gilbert-Jaramillo, J.,Zhang, C.,Saxena, A.,Huang, X.,Wang, H.,James, W.,Dwek, R.A.,Wilson, I.A.,Yang, G.,Lerner, R.A.; Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.; Adv Sci, 9:e2102181-e2102181, 2022; PubMed: 34716683; DOI: 10.1002/advs.202102181

実験手法

X-RAY DIFFRACTION (2.251 Å)