7KIS
Crystal structure of Pseudomonas aeruginosa PBP2 in complex with WCK 5153
Summary for 7KIS
Entry DOI | 10.2210/pdb7kis/pdb |
Descriptor | Peptidoglycan D,D-transpeptidase MrdA, (2S,5R)-1-formyl-N'-[(3R)-pyrrolidine-3-carbonyl]-5-[(sulfooxy)amino]piperidine-2-carbohydrazide, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | inhibitor, cell wall, antibiotic resistance, hydrolase, hydrolase-inhibitor-antibiotic complex, hydrolase/inhibitor/antibiotic |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 145414.87 |
Authors | Rajavel, M.,van den Akker, F. (deposition date: 2020-10-24, release date: 2021-01-13, Last modification date: 2023-10-18) |
Primary citation | Rajavel, M.,Kumar, V.,Nguyen, H.,Wyatt, J.,Marshall, S.H.,Papp-Wallace, K.M.,Deshpande, P.,Bhavsar, S.,Yeole, R.,Bhagwat, S.,Patel, M.,Bonomo, R.A.,van den Akker, F. Structural Characterization of Diazabicyclooctane beta-Lactam "Enhancers" in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa. Mbio, 12:-, 2021 Cited by PubMed: 33593978DOI: 10.1128/mBio.03058-20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.869 Å) |
Structure validation
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