7KFN
Structure of Human Adenosine Deaminase Acting on dsRNA (ADAR2) bound to dsRNA containing a 2'-deoxy Benner's Base Z opposite the edited base
Summary for 7KFN
Entry DOI | 10.2210/pdb7kfn/pdb |
Descriptor | Double-stranded RNA-specific editase 1, Gli1 8AZ 23mer RNA, Gli1 1W5 23mer RNA, ... (6 entities in total) |
Functional Keywords | rna binding protein, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 106240.56 |
Authors | Wilcox, X.E.,Fisher, A.J.,Beal, P.A. (deposition date: 2020-10-14, release date: 2021-06-16, Last modification date: 2023-10-18) |
Primary citation | Doherty, E.E.,Wilcox, X.E.,van Sint Fiet, L.,Kemmel, C.,Turunen, J.J.,Klein, B.,Tantillo, D.J.,Fisher, A.J.,Beal, P.A. Rational Design of RNA Editing Guide Strands: Cytidine Analogs at the Orphan Position. J.Am.Chem.Soc., 143:6865-6876, 2021 Cited by PubMed: 33939417DOI: 10.1021/jacs.0c13319 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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