7KFN

Structure of Human Adenosine Deaminase Acting on dsRNA (ADAR2) bound to dsRNA containing a 2'-deoxy Benner's Base Z opposite the edited base

Summary for 7KFN

• Entry DOI: 10.2210/pdb7kfn/pdb
• Descriptor: Double-stranded RNA-specific editase 1, Gli1 8AZ 23mer RNA, Gli1 1W5 23mer RNA, ... (6 entities in total)
• Functional Keywords: rna binding protein, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 106240.56

Authors

Wilcox, X.E.,Fisher, A.J.,Beal, P.A. (deposition date: 2020-10-14, release date: 2021-06-16, Last modification date: 2023-10-18)

• Primary citation: Doherty, E.E.,Wilcox, X.E.,van Sint Fiet, L.,Kemmel, C.,Turunen, J.J.,Klein, B.,Tantillo, D.J.,Fisher, A.J.,Beal, P.A.; Rational Design of RNA Editing Guide Strands: Cytidine Analogs at the Orphan Position.; J.Am.Chem.Soc., 143:6865-6876, 2021; PubMed: 33939417; DOI: 10.1021/jacs.0c13319

Experimental method

X-RAY DIFFRACTION (2.5 Å)