7KDT

Human Tom70 in complex with SARS CoV2 Orf9b

Summary for 7KDT

• Entry DOI: 10.2210/pdb7kdt/pdb
• EMDB information: 22829
• Descriptor: Mitochondrial import receptor subunit TOM70, ORF9b protein (2 entities in total)
• Functional Keywords: orf9b, tom70, mitochondria, virus infection, sars cov2, viral protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 67684.36

Authors

QCRG Structural Biology Consortium (deposition date: 2020-10-09, release date: 2020-10-21, Last modification date: 2024-03-06)

• Primary citation: Gordon, D.E.,Hiatt, J.,Bouhaddou, M.,Rezelj, V.V.,Ulferts, S.,Braberg, H.,Jureka, A.S.,Obernier, K.,Guo, J.Z.,Batra, J.,Kaake, R.M.,Weckstein, A.R.,Owens, T.W.,Gupta, M.,Pourmal, S.,Titus, E.W.,Cakir, M.,Soucheray, M.,McGregor, M.,Cakir, Z.,Jang, G.,O'Meara, M.J.,Tummino, T.A.,Zhang, Z.,Foussard, H.,Rojc, A.,Zhou, Y.,Kuchenov, D.,Huttenhain, R.,Xu, J.,Eckhardt, M.,Swaney, D.L.,Fabius, J.M.,Ummadi, M.,Tutuncuoglu, B.,Rathore, U.,Modak, M.,Haas, P.,Haas, K.M.,Naing, Z.Z.C.,Pulido, E.H.,Shi, Y.,Barrio-Hernandez, I.,Memon, D.,Petsalaki, E.,Dunham, A.,Marrero, M.C.,Burke, D.,Koh, C.,Vallet, T.,Silvas, J.A.,Azumaya, C.M.,Billesbolle, C.,Brilot, A.F.,Campbell, M.G.,Diallo, A.,Dickinson, M.S.,Diwanji, D.,Herrera, N.,Hoppe, N.,Kratochvil, H.T.,Liu, Y.,Merz, G.E.,Moritz, M.,Nguyen, H.C.,Nowotny, C.,Puchades, C.,Rizo, A.N.,Schulze-Gahmen, U.,Smith, A.M.,Sun, M.,Young, I.D.,Zhao, J.,Asarnow, D.,Biel, J.,Bowen, A.,Braxton, J.R.,Chen, J.,Chio, C.M.,Chio, U.S.,Deshpande, I.,Doan, L.,Faust, B.,Flores, S.,Jin, M.,Kim, K.,Lam, V.L.,Li, F.,Li, J.,Li, Y.L.,Li, Y.,Liu, X.,Lo, M.,Lopez, K.E.,Melo, A.A.,Moss 3rd, F.R.,Nguyen, P.,Paulino, J.,Pawar, K.I.,Peters, J.K.,Pospiech Jr., T.H.,Safari, M.,Sangwan, S.,Schaefer, K.,Thomas, P.V.,Thwin, A.C.,Trenker, R.,Tse, E.,Tsui, T.K.M.,Wang, F.,Whitis, N.,Yu, Z.,Zhang, K.,Zhang, Y.,Zhou, F.,Saltzberg, D.,Hodder, A.J.,Shun-Shion, A.S.,Williams, D.M.,White, K.M.,Rosales, R.,Kehrer, T.,Miorin, L.,Moreno, E.,Patel, A.H.,Rihn, S.,Khalid, M.M.,Vallejo-Gracia, A.,Fozouni, P.,Simoneau, C.R.,Roth, T.L.,Wu, D.,Karim, M.A.,Ghoussaini, M.,Dunham, I.,Berardi, F.,Weigang, S.,Chazal, M.,Park, J.,Logue, J.,McGrath, M.,Weston, S.,Haupt, R.,Hastie, C.J.,Elliott, M.,Brown, F.,Burness, K.A.,Reid, E.,Dorward, M.,Johnson, C.,Wilkinson, S.G.,Geyer, A.,Giesel, D.M.,Baillie, C.,Raggett, S.,Leech, H.,Toth, R.,Goodman, N.,Keough, K.C.,Lind, A.L.,Klesh, R.J.,Hemphill, K.R.,Carlson-Stevermer, J.,Oki, J.,Holden, K.,Maures, T.,Pollard, K.S.,Sali, A.,Agard, D.A.,Cheng, Y.,Fraser, J.S.,Frost, A.,Jura, N.,Kortemme, T.,Manglik, A.,Southworth, D.R.,Stroud, R.M.,Alessi, D.R.,Davies, P.,Frieman, M.B.,Ideker, T.,Abate, C.,Jouvenet, N.,Kochs, G.,Shoichet, B.,Ott, M.,Palmarini, M.,Shokat, K.M.,Garcia-Sastre, A.,Rassen, J.A.,Grosse, R.,Rosenberg, O.S.,Verba, K.A.,Basler, C.F.,Vignuzzi, M.,Peden, A.A.,Beltrao, P.,Krogan, N.J.; Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.; Science, 370:-, 2020; PubMed: 33060197; DOI: 10.1126/science.abe9403

Experimental method

ELECTRON MICROSCOPY (3.05 Å)