7KCZ

CRYSTAL STRUCTURE OF RHESUS MACAQUE (MACACA MULATTA) IGG1 FC FRAGMENT- FC-GAMMA RECEPTOR III COMPLEX V158 MUTANT

7KCZ の概要

• エントリーDOI: 10.2210/pdb7kcz/pdb
• 分子名称: IgG1 Fc, Low affinity immunoglobulin gamma Fc region receptor III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: immunoglobulin, igg1, immune system, immunoglobulin-like beta sandwich, fc fragment, fc gamma receptor iii
• 由来する生物種: Macaca mulatta (Rhesus macaque); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 152742.58

構造登録者

Tolbert, W.D.,Pazgier, M. (登録日: 2020-10-07, 公開日: 2021-10-13, 最終更新日: 2023-10-18)

• 主引用文献: Tolbert, W.D.,Gohain, N.,Kremer, P.G.,Hederman, A.P.,Nguyen, D.N.,Van, V.,Sherburn, R.,Lewis, G.K.,Finzi, A.,Pollara, J.,Ackerman, M.E.,Barb, A.W.,Pazgier, M.; Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques.; Front Immunol, 13:960411-960411, 2022; PubMed: 36131913; DOI: 10.3389/fimmu.2022.960411

実験手法

X-RAY DIFFRACTION (3.15 Å)