7KC1

Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA

Summary for 7KC1

• Entry DOI: 10.2210/pdb7kc1/pdb
• EMDB information: 22804
• Descriptor: Hemagglutinin, Fusion protein of Hemagglutinin and Envelope glycoprotein, Fab heavy chain, ... (7 entities in total)
• Functional Keywords: flu, ha, hv6-1, vrc, immune system, immune system-viral protein complex
• Biological source: Influenza A virus; More
• Total number of polymer chains: 12
• Total formula weight: 344828.60

Authors

Gorman, J.,Kwong, P.D. (deposition date: 2020-10-04, release date: 2021-05-12, Last modification date: 2021-07-14)

• Primary citation: Chuang, G.Y.,Shen, C.H.,Cheung, C.S.,Gorman, J.,Creanga, A.,Joyce, M.G.,Leung, K.,Rawi, R.,Wang, L.,Yang, E.S.,Yang, Y.,Zhang, B.,Zhang, Y.,Kanekiyo, M.,Zhou, T.,DeKosky, B.J.,Graham, B.S.,Mascola, J.R.,Kwong, P.D.; Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses.; Front Immunol, 12:662909-662909, 2021; PubMed: 34135892; DOI: 10.3389/fimmu.2021.662909

Experimental method

ELECTRON MICROSCOPY (3.41 Å)