7KC1

Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA

7KC1 の概要

• エントリーDOI: 10.2210/pdb7kc1/pdb
• EMDBエントリー: 22804
• 分子名称: Hemagglutinin, Fusion protein of Hemagglutinin and Envelope glycoprotein, Fab heavy chain, ... (7 entities in total)
• 機能のキーワード: flu, ha, hv6-1, vrc, immune system, immune system-viral protein complex
• 由来する生物種: Influenza A virus; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 344828.60

構造登録者

Gorman, J.,Kwong, P.D. (登録日: 2020-10-04, 公開日: 2021-05-12, 最終更新日: 2021-07-14)

• 主引用文献: Chuang, G.Y.,Shen, C.H.,Cheung, C.S.,Gorman, J.,Creanga, A.,Joyce, M.G.,Leung, K.,Rawi, R.,Wang, L.,Yang, E.S.,Yang, Y.,Zhang, B.,Zhang, Y.,Kanekiyo, M.,Zhou, T.,DeKosky, B.J.,Graham, B.S.,Mascola, J.R.,Kwong, P.D.; Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses.; Front Immunol, 12:662909-662909, 2021; PubMed: 34135892; DOI: 10.3389/fimmu.2021.662909

実験手法

ELECTRON MICROSCOPY (3.41 Å)