7KBC
The crystal structure of the 2009/H1N1/California PA endonuclease mutant E119D (construct with truncated loop 51-72) in complex with baloxavir acid
Summary for 7KBC
| Entry DOI | 10.2210/pdb7kbc/pdb |
| Related | 6W5P 7K0W 7KAF |
| Descriptor | Protein PA-X, Baloxavir acid, Hexa Vinylpyrrolidone K15, ... (7 entities in total) |
| Functional Keywords | nuclease, influenza, cleaved, viral protein, dna binding protein |
| Biological source | Influenza A virus More |
| Total number of polymer chains | 1 |
| Total formula weight | 24953.08 |
| Authors | Cuypers, M.G.,Kumar, G.,Slavish, J.,White, S.W. (deposition date: 2020-10-02, release date: 2021-02-03, Last modification date: 2023-10-18) |
| Primary citation | Kumar, G.,Cuypers, M.,Webby, R.R.,Webb, T.R.,White, S.W. Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism. Nucleic Acids Res., 49:1609-1618, 2021 Cited by PubMed: 33469660DOI: 10.1093/nar/gkaa1294 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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