7K75

Crystal structure of MAD2-6 IgA Fab in complex with PfCSP N-terminal peptide.

Summary for 7K75

• Entry DOI: 10.2210/pdb7k75/pdb
• Descriptor: Heavy chain of MAD2-6 IgA Fab, Light chain of MAD2-6 IgA Fab, PfCSP N-terminal peptide P17, ... (4 entities in total)
• Functional Keywords: malaria, circumsporozoite protein, n-terminal domain, region i, antibody, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 10
• Total formula weight: 192276.71

Authors

Pholcharee, T.,Wilson, I.A. (deposition date: 2020-09-22, release date: 2021-06-23, Last modification date: 2024-04-03)

• Primary citation: Tan, J.,Cho, H.,Pholcharee, T.,Pereira, L.S.,Doumbo, S.,Doumtabe, D.,Flynn, B.J.,Schon, A.,Kanatani, S.,Aylor, S.O.,Oyen, D.,Vistein, R.,Wang, L.,Dillon, M.,Skinner, J.,Peterson, M.,Li, S.,Idris, A.H.,Molina-Cruz, A.,Zhao, M.,Olano, L.R.,Lee, P.J.,Roth, A.,Sinnis, P.,Barillas-Mury, C.,Kayentao, K.,Ongoiba, A.,Francica, J.R.,Traore, B.,Wilson, I.A.,Seder, R.A.,Crompton, P.D.; Functional human IgA targets a conserved site on malaria sporozoites.; Sci Transl Med, 13:-, 2021; PubMed: 34162751; DOI: 10.1126/scitranslmed.abg2344

Experimental method

X-RAY DIFFRACTION (2.5 Å)