7K6P
Active state Dot1 bound to the unacetylated H4 nucleosome
Summary for 7K6P
Entry DOI | 10.2210/pdb7k6p/pdb |
EMDB information | 22691 22692 22693 22694 22695 |
Descriptor | Histone H3.2, Histone H4, Histone H2A type 1, ... (9 entities in total) |
Functional Keywords | structural protein/dna/transferase, transferase, structural protein-dna-transferase complex |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 12 |
Total formula weight | 233348.82 |
Authors | Valencia-Sanchez, M.I.,De Ioannes, P.E.,Miao, W.,Truong, D.M.,Lee, R.,Armache, J.-P.,Boeke, J.D.,Armache, K.-J. (deposition date: 2020-09-21, release date: 2021-02-10, Last modification date: 2024-03-06) |
Primary citation | Valencia-Sanchez, M.I.,De Ioannes, P.,Wang, M.,Truong, D.M.,Lee, R.,Armache, J.P.,Boeke, J.D.,Armache, K.J. Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation. Science, 371:-, 2021 Cited by PubMed: 33479126DOI: 10.1126/science.abc6663 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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