7K43
SARS-CoV-2 spike in complex with the S2M11 neutralizing antibody Fab fragment
Summary for 7K43
Entry DOI | 10.2210/pdb7k43/pdb |
EMDB information | 22659 |
Descriptor | Spike glycoprotein, S2M11 Fab fragment (heavy chain), S2M11 Fab fragment (light chain), ... (6 entities in total) |
Functional Keywords | sars-cov-2, covid-19, spike glycoprotein, fusion protein, neutralizing antibodies, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 9 |
Total formula weight | 518062.43 |
Authors | Tortorici, M.A.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2020-09-14, release date: 2020-10-07, Last modification date: 2021-01-27) |
Primary citation | Tortorici, M.A.,Beltramello, M.,Lempp, F.A.,Pinto, D.,Dang, H.V.,Rosen, L.E.,McCallum, M.,Bowen, J.,Minola, A.,Jaconi, S.,Zatta, F.,De Marco, A.,Guarino, B.,Bianchi, S.,Lauron, E.J.,Tucker, H.,Zhou, J.,Peter, A.,Havenar-Daughton, C.,Wojcechowskyj, J.A.,Case, J.B.,Chen, R.E.,Kaiser, H.,Montiel-Ruiz, M.,Meury, M.,Czudnochowski, N.,Spreafico, R.,Dillen, J.,Ng, C.,Sprugasci, N.,Culap, K.,Benigni, F.,Abdelnabi, R.,Foo, S.C.,Schmid, M.A.,Cameroni, E.,Riva, A.,Gabrieli, A.,Galli, M.,Pizzuto, M.S.,Neyts, J.,Diamond, M.S.,Virgin, H.W.,Snell, G.,Corti, D.,Fink, K.,Veesler, D. Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms. Science, 370:950-957, 2020 Cited by PubMed: 32972994DOI: 10.1126/science.abe3354 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.6 Å) |
Structure validation
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