7K3Y
GGYAGAS segment 52-58 from Keratin-8
Summary for 7K3Y
Entry DOI | 10.2210/pdb7k3y/pdb |
Related | 7K3C |
Descriptor | GGYAGAS segment 52-58 from the low complexity domain of Keratin-8 (2 entities in total) |
Functional Keywords | amyloid filament, low complexity sequence, protein fibril |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 1163.16 |
Authors | Murray, K.A.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2020-09-14, release date: 2021-11-10, Last modification date: 2024-04-03) |
Primary citation | Murray, K.A.,Hughes, M.P.,Hu, C.J.,Sawaya, M.R.,Salwinski, L.,Pan, H.,French, S.W.,Seidler, P.M.,Eisenberg, D.S. Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat.Struct.Mol.Biol., 29:529-536, 2022 Cited by PubMed: 35637421DOI: 10.1038/s41594-022-00774-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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