7K3R
Cryo-EM structure of AIM2-PYD filament
Summary for 7K3R
Entry DOI | 10.2210/pdb7k3r/pdb |
EMDB information | 22656 |
Descriptor | Interferon-inducible protein AIM2 (1 entity in total) |
Functional Keywords | inflammasome, aim2 filament, helical reconstruction, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 21 |
Total formula weight | 284101.76 |
Authors | Zheng, W.,Matyszewski, M.,Sohn, J.,Egelman, E.H. (deposition date: 2020-09-12, release date: 2021-05-26, Last modification date: 2024-03-06) |
Primary citation | Matyszewski, M.,Zheng, W.,Lueck, J.,Mazanek, Z.,Mohideen, N.,Lau, A.Y.,Egelman, E.H.,Sohn, J. Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome. Nat Commun, 12:2735-2735, 2021 Cited by PubMed: 33980849DOI: 10.1038/s41467-021-23045-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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