7K1E

Crystal structure of human insulin degrading enzyme (IDE) in complex with compound BDM_88646

7K1E の概要

• エントリーDOI: 10.2210/pdb7k1e/pdb
• 分子名称: Insulin-degrading enzyme, ZINC ION, 3,4-difluoro-N-[(1S)-1-{1-[(2R)-4-(hydroxyamino)-4-oxo-1-(5,6,7,8-tetrahydronaphthalen-2-yl)butan-2-yl]-1H-1,2,3-triazol-4-yl}ethyl]benzamide, ... (6 entities in total)
• 機能のキーワード: hydrolase, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 231226.20

構造登録者

Liang, W.G.,Deprez, R.,Bosc, D.,Tang, W. (登録日: 2020-09-07, 公開日: 2021-09-22, 最終更新日: 2023-10-18)

• 主引用文献: Liang, W.G.,Deprez, R.,Bosc, D.,Tang, W.; Crystal structure of human insulin degrading enzyme (IDE) in complex with compound 3; To Be Published,

実験手法

X-RAY DIFFRACTION (2.8 Å)