7K1D

Crystal structure of human insulin degrading enzyme (IDE) in complex with compound BDM_77291

7K1D の概要

• エントリーDOI: 10.2210/pdb7k1d/pdb
• 分子名称: Insulin-degrading enzyme, ZINC ION, (3R)-3-{4-[(3R)-4-(3,4-difluorobenzene-1-carbonyl)morpholin-3-yl]-1H-1,2,3-triazol-1-yl}-N-hydroxy-4-(naphthalen-2-yl)butanamide, ... (5 entities in total)
• 機能のキーワード: hydrolase, inhibitor, hydrolase-hydrolase inhbitor complex, hydrolase/hydrolase inhbitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 231302.21

構造登録者

Liang, W.G.,Deprez, R.,Bosc, D.,Tang, W. (登録日: 2020-09-07, 公開日: 2021-09-22, 最終更新日: 2023-10-18)

• 主引用文献: Liang, W.G.,Deprez, R.,Bosc, D.,Tang, W.; Crystal structure of human insulin degrading enzyme (IDE) in complex with compound 2; To Be Published,

実験手法

X-RAY DIFFRACTION (3 Å)