7K0I
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa
Summary for 7K0I
Entry DOI | 10.2210/pdb7k0i/pdb |
EMDB information | 22598 |
Descriptor | Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, Serine palmitoyltransferase small subunit A, ... (5 entities in total) |
Functional Keywords | sphingolipid, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 247794.12 |
Authors | Wang, Y.,Niu, Y.,Zhang, Z.,Zhao, H.,Myasnikov, A.,Kalathur, R.,Lee, C.H. (deposition date: 2020-09-04, release date: 2021-02-24, Last modification date: 2021-03-24) |
Primary citation | Wang, Y.,Niu, Y.,Zhang, Z.,Gable, K.,Gupta, S.D.,Somashekarappa, N.,Han, G.,Zhao, H.,Myasnikov, A.G.,Kalathur, R.C.,Dunn, T.M.,Lee, C.H. Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28:240-248, 2021 Cited by PubMed: 33558761DOI: 10.1038/s41594-020-00551-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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