7JYD

Human Liver Receptor Homolog-1 in Complex with 10CA and a Fragment of Tif2

7JYD の概要

• エントリーDOI: 10.2210/pdb7jyd/pdb
• 分子名称: Nuclear receptor subfamily 5 group A member 2, Nuclear receptor coactivator 2, 10-[(3aR,6R,6aR)-6-hydroxy-3-phenyl-3a-(1-phenylethenyl)-1,3a,4,5,6,6a-hexahydropentalen-2-yl]decanoic acid, ... (4 entities in total)
• 機能のキーワード: agonist, nuclear receptor, transcription
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30353.19

構造登録者

D'Agostino, E.H.,Mays, S.G.,Ortlund, E.A. (登録日: 2020-08-30, 公開日: 2022-03-02, 最終更新日: 2023-10-18)

• 主引用文献: D'Agostino, E.H.,Mays, S.G.,Flynn, A.F.,Huang, X.,Wang, G.,Liu, X.,Millings, E.J.,Okafor, C.D.,Patel, A.,Cato, M.L.,Cornelison, J.C.,Houtman, R.,Moore, D.D.,Calvert, J.W.,Jui, N.T.,Ortlund, E.A.; Tapping into a phospholipid-LRH-1 axis yields a powerful anti-inflammatory agent with in vivo activity against colitis; To Be Published,

実験手法

X-RAY DIFFRACTION (2.3 Å)