7JYA
Crystal structure of E3 ligase in complex with peptide
Summary for 7JYA
Entry DOI | 10.2210/pdb7jya/pdb |
Descriptor | Protein fem-1 homolog C, ASN-ARG-ARG-ARG-ARG-TRP-ARG-GLU-ARG-GLN-ARG, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | ups, ubiquitin, e3 ligase, protein degradation, structural genomics, structural genomics consortium, sgc, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 128304.13 |
Authors | Yan, X.,Dong, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Min, J.R.,Dong, C.,Structural Genomics Consortium (SGC) (deposition date: 2020-08-30, release date: 2020-10-14, Last modification date: 2023-10-18) |
Primary citation | Yan, X.,Wang, X.,Li, Y.,Zhou, M.,Li, Y.,Song, L.,Mi, W.,Min, J.,Dong, C. Molecular basis for ubiquitin ligase CRL2 FEM1C -mediated recognition of C-degron. Nat.Chem.Biol., 17:263-271, 2021 Cited by PubMed: 33398170DOI: 10.1038/s41589-020-00703-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.46 Å) |
Structure validation
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