7JXO

Triangular trimer of beta-hairpins derived from Abeta17-36 with an F20Cha mutation

7JXO の概要

• エントリーDOI: 10.2210/pdb7jxo/pdb
• 分子名称: Amyloid-beta 17-36 peptide (2 entities in total)
• 機能のキーワード: amyloid, oligomer, alzheimer's disease, beta-hairpin, de novo protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 6662.03

構造登録者

Kreutzer, A.G.,Haerianardakani, S.,Nowick, J.S. (登録日: 2020-08-27, 公開日: 2020-12-09, 最終更新日: 2023-10-18)

• 主引用文献: Haerianardakani, S.,Kreutzer, A.G.,Salveson, P.J.,Samdin, T.D.,Guaglianone, G.E.,Nowick, J.S.; Phenylalanine Mutation to Cyclohexylalanine Facilitates Triangular Trimer Formation by beta-Hairpins Derived from A beta.; J.Am.Chem.Soc., 142:20708-20716, 2020; PubMed: 33237748; DOI: 10.1021/jacs.0c09281

実験手法

X-RAY DIFFRACTION (2.81 Å)