7JX3

Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology

7JX3 の概要

• エントリーDOI: 10.2210/pdb7jx3/pdb
• 分子名称: Light chain of Fab domain of monoclonal antibody S309, Heavy chain of Fab domain of monoclonal antibody S309, Light chain of Fab domain of monoclonal antibody S2H14, ... (9 entities in total)
• 機能のキーワード: covid-19, sars-cov-2, neutralizing monoclonal antibody, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 165433.84

構造登録者

Snell, G.,Czudnochowski, N.,Rosen, L.E.,Nix, J.C.,Corti, D.,Veesler, D.,Park, Y.J.,Walls, A.C.,Tortorici, M.A.,Cameroni, E.,Pinto, D.,Beltramello, M.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2020-08-26, 公開日: 2020-10-14, 最終更新日: 2023-10-18)

• 主引用文献: Piccoli, L.,Park, Y.J.,Tortorici, M.A.,Czudnochowski, N.,Walls, A.C.,Beltramello, M.,Silacci-Fregni, C.,Pinto, D.,Rosen, L.E.,Bowen, J.E.,Acton, O.J.,Jaconi, S.,Guarino, B.,Minola, A.,Zatta, F.,Sprugasci, N.,Bassi, J.,Peter, A.,De Marco, A.,Nix, J.C.,Mele, F.,Jovic, S.,Rodriguez, B.F.,Gupta, S.V.,Jin, F.,Piumatti, G.,Lo Presti, G.,Pellanda, A.F.,Biggiogero, M.,Tarkowski, M.,Pizzuto, M.S.,Cameroni, E.,Havenar-Daughton, C.,Smithey, M.,Hong, D.,Lepori, V.,Albanese, E.,Ceschi, A.,Bernasconi, E.,Elzi, L.,Ferrari, P.,Garzoni, C.,Riva, A.,Snell, G.,Sallusto, F.,Fink, K.,Virgin, H.W.,Lanzavecchia, A.,Corti, D.,Veesler, D.; Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.; Cell, 183:1024-1042.e21, 2020; PubMed: 32991844; DOI: 10.1016/j.cell.2020.09.037

実験手法

X-RAY DIFFRACTION (2.65 Å)