7JU8
X-ray structure of MMP-13 in Complex with 4-(1,2,3-thiadiazol-4-yl)pyridine
Summary for 7JU8
Entry DOI | 10.2210/pdb7ju8/pdb |
Descriptor | Collagenase 3, ZINC ION, CALCIUM ION, ... (8 entities in total) |
Functional Keywords | protease, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 40069.79 |
Authors | Farrow, N.A. (deposition date: 2020-08-19, release date: 2021-08-04, Last modification date: 2023-10-18) |
Primary citation | Taylor, S.J.,Abeywardane, A.,Liang, S.,Xiong, Z.,Proudfoot, J.R.,Farmer, B.S.,Gao, D.A.,Heim-Riether, A.,Smith-Keenan, L.L.,Muegge, I.,Yu, Y.,Zhang, Q.,Souza, D.,Panzenbeck, M.,Goldberg, D.,Hill-Drzewi, M.,Margarit, M.,Collins, B.,Li, J.X.,Zuvela-Jelaska, L.,Li, J.,Farrow, N.A. Indole Inhibitors of MMP-13 for Arthritic Disorders Acs Omega, 6:18635-18650, 2021 Cited by DOI: 10.1021/acsomega.1c01320PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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