7JTG

Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody RM11-43

7JTG の概要

• エントリーDOI: 10.2210/pdb7jtg/pdb
• 分子名称: RM11-43 Fab heavy chain, RM11-43 Fab light chain, Envelope glycoprotein E2, ... (6 entities in total)
• 機能のキーワード: hcv, broadly neutralizing antibodies, bnabs, e2 core, ighv1-69, immune system, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Macaca mulatta; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 68909.19

構造登録者

Tzarum, N.,Wilson, I.A.,Law, M. (登録日: 2020-08-17, 公開日: 2021-03-10, 最終更新日: 2023-10-18)

• 主引用文献: Tzarum, N.,Chen, F.,Lin, X.,Giang, E.,Velazquez-Moctezuma, R.,Augestad, E.H.,Nagy, K.,He, L.,Davidson, E.,Chavez, D.,Prentoe, J.,Stanfield, R.L.,Lanford, R.,Bukh, J.,Wilson, I.A.,Zhu, J.,Law, M.; HCV Env immunization elicits a rapid VH1-69-like broadly neutralizing antibody response in rhesus macaques; Immunity, 2021

実験手法

X-RAY DIFFRACTION (2.6 Å)