7JQR

Abeta 16-36 beta-hairpin mimic with E22G Arctic mutation

Summary for 7JQR

Entry DOI	10.2210/pdb7jqr/pdb
Descriptor	Abeta 16-36 beta-hairpin mimic VAL-ORN-LYS-LEU-VAL-MEA-PHE-ALA-GLY-ORN-ALA-ILE-ILE-GLY-LEU-MET, IODIDE ION (3 entities in total)
Functional Keywords	alzheimer's disease, amyloid, abeta, oligomer, familial mutant, de novo protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	2102.92
Authors	Kreutzer, A.G.,McKnelly, K.J.,Nowick, J.S. (deposition date: 2020-08-11, release date: 2021-09-08, Last modification date: 2022-03-30)
Primary citation	McKnelly, K.J.,Kreutzer, A.G.,Howitz, W.J.,Haduong, K.,Yoo, S.,Hart, C.,Nowick, J.S. Effects of Familial Alzheimer's Disease Mutations on the Assembly of a beta-Hairpin Peptide Derived from A beta 16-36 . Biochemistry, 61:446-454, 2022 Cited by PubMed: 35213141 DOI: 10.1021/acs.biochem.1c00664 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.07 Å)

Structure validation