7JPN

Cryo-EM structure of Arpin-bound Arp2/3 complex

Summary for 7JPN

• Entry DOI: 10.2210/pdb7jpn/pdb
• EMDB information: 22416
• Descriptor: Actin-related protein 3, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, ... (10 entities in total)
• Functional Keywords: actin, atpase, actin related protein, arp, cytoskeleton, arp2-3 complex, actin nucleation, actin branching, contractile protein, arpin
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 225823.59

Authors

van Eeuwen, T.,Fregoso, F.E.,Dominguez, R.,Zimmet, A.,Boczkowska, M.,Rebowski, G. (deposition date: 2020-08-09, release date: 2022-02-09, Last modification date: 2024-05-15)

• Primary citation: Fregoso, F.E.,van Eeuwen, T.,Simanov, G.,Rebowski, G.,Boczkowska, M.,Zimmet, A.,Gautreau, A.M.,Dominguez, R.; Molecular mechanism of Arp2/3 complex inhibition by Arpin.; Nat Commun, 13:628-628, 2022; PubMed: 35110533; DOI: 10.1038/s41467-022-28112-2

Experimental method

ELECTRON MICROSCOPY (3.24 Å)