7JLR
Crystal structure of Bacillus subtilis UppS in complex with JPD447
Summary for 7JLR
Entry DOI | 10.2210/pdb7jlr/pdb |
Related | 7JLI |
Descriptor | Isoprenyl transferase, 7-(azepan-1-yl)-5-ethyl-3-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine (3 entities in total) |
Functional Keywords | undecaprenyl, cis-prenyltransferase, carrier lipid, jpd447, transferase |
Biological source | Bacillus subtilis |
Total number of polymer chains | 1 |
Total formula weight | 30152.54 |
Authors | Workman, S.D.,Strynadka, N.C.J. (deposition date: 2020-07-30, release date: 2021-08-04, Last modification date: 2023-10-18) |
Primary citation | Workman, S.D.,Day, J.,Farha, M.A.,El Zahed, S.S.,Bon, C.,Brown, E.D.,Organ, M.G.,Strynadka, N.C.J. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. J.Med.Chem., 64:13540-13550, 2021 Cited by PubMed: 34473495DOI: 10.1021/acs.jmedchem.1c00941 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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