7JKX
Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6
Summary for 7JKX
Entry DOI | 10.2210/pdb7jkx/pdb |
Descriptor | Bromodomain-containing protein 4, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-[1-methyl-5-(methylamino)-6-oxo-1,6-dihydropyridin-3-yl]-1H-indol-4-yl}ethanesulfonamide (3 entities in total) |
Functional Keywords | pan bds inhibitor, transcription, structural genomics, seattle structural genomics center for infectious disease, ssgcid |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15666.03 |
Authors | Ratia, K.M.,Xiong, R.,Li, Y.,Shen, Z.,Zhao, J.,Huang, F.,Dubrovyskyii, O.,Thatcher, G.R. (deposition date: 2020-07-29, release date: 2021-06-23, Last modification date: 2023-10-18) |
Primary citation | Xiong, R.,Ratia, K.M.,Li, Y.,Shen, Z.,Zhao, J.,Huang, F.,Dubrovyskyii, O.,Thatcher, G.R. Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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