7JKX

Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6

Summary for 7JKX

• Entry DOI: 10.2210/pdb7jkx/pdb
• Descriptor: Bromodomain-containing protein 4, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-[1-methyl-5-(methylamino)-6-oxo-1,6-dihydropyridin-3-yl]-1H-indol-4-yl}ethanesulfonamide (3 entities in total)
• Functional Keywords: pan bds inhibitor, transcription, structural genomics, seattle structural genomics center for infectious disease, ssgcid
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 15666.03

Authors

Ratia, K.M.,Xiong, R.,Li, Y.,Shen, Z.,Zhao, J.,Huang, F.,Dubrovyskyii, O.,Thatcher, G.R. (deposition date: 2020-07-29, release date: 2021-06-23, Last modification date: 2023-10-18)

• Primary citation: Xiong, R.,Ratia, K.M.,Li, Y.,Shen, Z.,Zhao, J.,Huang, F.,Dubrovyskyii, O.,Thatcher, G.R.; Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.2 Å)