7JKX

Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6

7JKX の概要

• エントリーDOI: 10.2210/pdb7jkx/pdb
• 分子名称: Bromodomain-containing protein 4, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-[1-methyl-5-(methylamino)-6-oxo-1,6-dihydropyridin-3-yl]-1H-indol-4-yl}ethanesulfonamide (3 entities in total)
• 機能のキーワード: pan bds inhibitor, transcription, structural genomics, seattle structural genomics center for infectious disease, ssgcid
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15666.03

構造登録者

Ratia, K.M.,Xiong, R.,Li, Y.,Shen, Z.,Zhao, J.,Huang, F.,Dubrovyskyii, O.,Thatcher, G.R. (登録日: 2020-07-29, 公開日: 2021-06-23, 最終更新日: 2023-10-18)

• 主引用文献: Xiong, R.,Ratia, K.M.,Li, Y.,Shen, Z.,Zhao, J.,Huang, F.,Dubrovyskyii, O.,Thatcher, G.R.; Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6; To Be Published,

実験手法

X-RAY DIFFRACTION (1.2 Å)