7JH6

De novo designed two-domain di-Zn(II) and porphyrin-binding protein

7JH6 の概要

• エントリーDOI: 10.2210/pdb7jh6/pdb
• 分子名称: Two-domain di-Zn(II) and porphyrin-binding protein, ZINC ION, [5,10,15,20-tetrakis(trifluoromethyl)porphyrinato(2-)-kappa~4~N~21~,N~22~,N~23~,N~24~]zinc, ... (5 entities in total)
• 機能のキーワード: metalloprotein, inter-domain coupling and cooperation, de novo protein design, allostery, synthetic porphyrin, de novo protein
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 86931.44

構造登録者

Schmidt, N.,Liu, L.,DeGrado, W.F. (登録日: 2020-07-20, 公開日: 2020-12-09, 最終更新日: 2024-04-03)

• 主引用文献: Pirro, F.,Schmidt, N.,Lincoff, J.,Widel, Z.X.,Polizzi, N.F.,Liu, L.,Therien, M.J.,Grabe, M.,Chino, M.,Lombardi, A.,DeGrado, W.F.; Allosteric cooperation in a de novo-designed two-domain protein.; Proc.Natl.Acad.Sci.USA, 117:33246-33253, 2020; PubMed: 33318174; DOI: 10.1073/pnas.2017062117

実験手法

X-RAY DIFFRACTION (3.5 Å)