7JG9
Cryo-EM structure of bedaquiline-saturated mycobacterium smegmatis ATP synthase rotational state 2 (backbone model)
Summary for 7JG9
Entry DOI | 10.2210/pdb7jg9/pdb |
EMDB information | 22311 22312 22313 22314 22315 22316 22317 22318 22319 22320 22321 22322 |
Descriptor | ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase gamma chain, ... (9 entities in total) |
Functional Keywords | bedaquiline, sirturo, tmc207, t207910, atp synthase, mycobacteria, tuberculosis, hydrolase |
Biological source | Mycolicibacterium smegmatis More |
Total number of polymer chains | 20 |
Total formula weight | 552563.60 |
Authors | Guo, H.,Courbon, G.M.,Rubinstein, J.L. (deposition date: 2020-07-18, release date: 2020-08-19, Last modification date: 2024-03-06) |
Primary citation | Guo, H.,Courbon, G.M.,Bueler, S.A.,Mai, J.,Liu, J.,Rubinstein, J.L. Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline. Nature, 589:143-147, 2021 Cited by PubMed: 33299175DOI: 10.1038/s41586-020-3004-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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