7H68

THE 1.25 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH (2R)-2-benzyl-4-[(R)-(5-fluoro-3-methyl-1H-indol-2-yl)-phenylmethyl]-3-hydroxy-2H-furan-5-one

This is a non-PDB format compatible entry.

Summary for 7H68

• Entry DOI: 10.2210/pdb7h68/pdb
• Group deposition: A set of chymase crystal structures for D3R plus two CatG off-target structures (G_1002292)
• Descriptor: Chymase, ZINC ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: human chymase, serine proteinase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 25816.33

Authors

Banner, D.W.,Benz, J.M.,Joseph, C.,Schlatter, D.,Hilpert, H. (deposition date: 2024-04-19, release date: 2025-03-05)

• Primary citation: Markus, R.,Tosstorff, A.; Crystal structures of human Chymase and Cathepsin G; To be published,

Experimental method

X-RAY DIFFRACTION (1.25 Å)