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7FYZ

Crystal Structure of human FABP4 in complex with 2-[2,3-bis[(2-chlorophenyl)methoxy]phenyl]-2-methoxyacetic acid, i.e. SMILES c1c(c(c(cc1)OCc1ccccc1Cl)OCc1c(cccc1)Cl)[C@@H](C(=O)O)OC with IC50=1.1 microM

Summary for 7FYZ
Entry DOI10.2210/pdb7fyz/pdb
Group depositionTo be published (G_1002264)
DescriptorFatty acid-binding protein, adipocyte, SULFATE ION, (2R)-{2,3-bis[(2-chlorophenyl)methoxy]phenyl}(methoxy)acetic acid, ... (4 entities in total)
Functional Keywordslipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight15661.61
Authors
Ehler, A.,Benz, J.,Obst, U.,Obst-Sander, U.,Rudolph, M.G. (deposition date: 2023-04-27, release date: 2023-06-14, Last modification date: 2024-11-20)
Primary citationObst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.
Crystal Structure of a human FABP4 complex
To be published,
Experimental method
X-RAY DIFFRACTION (1.13 Å)
Structure validation

239149

数据于2025-07-23公开中

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