7FX2

Crystal Structure of human FABP4 binding site mutated to that of FABP5 in complex with 2-[[6,6-difluoro-3-(4-methyl-1,3-thiazol-2-yl)-5,7-dihydro-4H-1-benzothiophen-2-yl]carbamoyl]cyclohexene-1-carboxylic acid

7FX2 の概要

• エントリーDOI: 10.2210/pdb7fx2/pdb
• Group deposition: To be published (G_1002264)
• 分子名称: Fatty acid-binding protein, adipocyte, 2-{[(3M)-6,6-difluoro-3-(4-methyl-1,3-thiazol-2-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]carbamoyl}cyclohex-1-ene-1-carboxylic acid (3 entities in total)
• 機能のキーワード: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15450.76

構造登録者

Ehler, A.,Benz, J.,Obst, U.,Richter, H.,Rudolph, M.G. (登録日: 2023-04-27, 公開日: 2023-06-14, 最終更新日: 2024-04-03)

• 主引用文献: Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.; Crystal Structure of a human FABP4 binding site mutated to that of FABP5 complex; To be published,

実験手法

X-RAY DIFFRACTION (1.47 Å)