7FUC

Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-4-methylphenyl)-2-(morpholin-4-ylmethyl)-1H-benzimidazole-4-carboxylic acid

7FUC の概要

• エントリーDOI: 10.2210/pdb7fuc/pdb
• Group deposition: To be published (G_1002263)
• 分子名称: Cyclic GMP-AMP synthase, ZINC ION, (6M)-6-(2-chloro-4-methylphenyl)-2-[(morpholin-4-yl)methyl]-1H-benzimidazole-4-carboxylic acid (3 entities in total)
• 機能のキーワード: immune response, transferase, ntase, dna sensor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42856.16

構造登録者

Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Galley, G.,Rudolph, M.G. (登録日: 2023-02-08, 公開日: 2024-02-21)

• 主引用文献: Groebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G.; Crystal Structure of a human cyclic GMP-AMP synthase complex; To be published,

実験手法

X-RAY DIFFRACTION (2.52 Å)